The central insight of Darwin's Origin of Species is that evolution is an ecological phenomenon, arising from the activities of organisms in the 'struggle for life'. By contrast, the Modern Synthesis theory of evolution, which rose to prominence in the twentieth century, presents evolution as a fundamentally molecular phenomenon, occurring in populations of sub-organismal entities - genes. After nearly a century of success, the Modern Synthesis theory is now being challenged by empirical advances in the study of organismal development and (...) inheritance. In this important study, D. M. Walsh shows that the principal defect of the Modern Synthesis resides in its rejection of Darwin's organismal perspective, and argues for 'situated Darwinism': an alternative, organism-centred conception of evolution that prioritises organisms as adaptive agents. His book will be of interest to scholars and advanced students of evolutionary biology and the philosophy of biology. (shrink)

Originally published in 1936, this book presents the ancient Greek text of the paraphrases and quotations of Zeno's philosophical arguments, together with a facing-page English translation and editorial commentary. Detailed notes are incorporated throughout and a bibliography is also included. This book will be of value to anyone with an interest in Zeno and ancient philosophy.

The subject of the present inquiry is the approach-to-the-truth research, which started with the publication of Sir Karl Popper's Conjectures and Refutations. In the decade before this publication, Popper fiercely attacked the ideas of Rudolf Carnap about confirmation and induction; and ten years later, in the famous tenth chapter of Conjectures he introduced his own ideas about scientific progress and verisimilitude. Abhorring inductivism for its apprecia tion of logical weakness rather than strength, Popper tried to show that fallibilism could serve (...) the purpose of approach to the truth. To substantiate this idea he formalized the common sense intuition about preferences, that is: B is to be preferred to A if B has more advantages andfewer drawbacks than A. In 1974, however, David Millerand Pavel Tichy proved that Popper's formal explication could not be used to compare false theories. Subsequently, many researchers proposed alternatives or tried to improve Popper's original definition. (shrink)

This article describes the process engaged by 17 expert scholars in the development of a set of six consensus recommendations about the normative foundations of pediatric decision-making. The process began with a robust pre-reading assignment, followed by three days of in-person symposium discussions that resulted in a publication in _Pediatrics_ entitled “Pediatric Decision-Making: Consensus Recommendations” (Salter et al. 2023). This article next compares the six recommendations to existing statements about pediatric decision-making (specifically those developed by the American Academy of Pediatrics), (...) highlighting similarities and differences. Finally, the article discusses the value of finding consensus in the field of pediatric bioethics. (shrink)

In this essay, I claim that certain passages in Book IV of Benedict de Spinoza’s Ethics suggest a novel version of what is known as metaethical constructivism. The constructivist interpretation emerges in the course of attempting to resolve a tension between Spinoza’s apparent ethical egoism and some remarks he makes about the efficacy of collaborating with the right partners when attempting to promote our individual self-interest . Though Spinoza maintains that individuals necessarily aim to promote their self-interest, I argue that (...) Spinoza has an atypical conception of self that allows the interests of other people to be partially constitutive of one's own self-interest. In this way, Spinoza can account for the rationality of concern for the interests of others . This interpretation attributes to Spinoza a form of constructivism that differs in important ways from contemporary Humean and Kantian constructivisms and which can in principle be detached from Spinoza’s particular metaphysical commitments in order to yield a third general category of constructivist view . Though my treatment is necessarily brief, it is my hope that it can serve both to motivate a constructivist reading of Spinoza and, perhaps even more crucially, to suggest a Spinozistic variety of constructivism as a live theoretical option in metaethics. (shrink)

Both the concept of a Darwinian tree of life (TOL) and the possibility of its accurate reconstruction have been much criticized. Criticisms mostly revolve around the extensive occurrence of lateral gene transfer (LGT), instances of uptake of complete organisms to become organelles (with the associated subsequent gene transfer to the nucleus), as well as the implications of more subtle aspects of the biological species concept. Here we argue that none of these criticisms are sufficient to abandon the valuable TOL concept (...) and the biological realities it captures. Especially important is the need to conceptually distinguish between organismal trees and gene trees, which necessitates incorporating insights of widely occurring LGT into modern evolutionary theory. We demonstrate that all criticisms, while based on important new findings, do not invalidate the TOL. After considering the implications of these new insights, we find that the contours of evolution are best represented by a TOL. (shrink)

Antimicrobial resistance (AMR) poses an increasing threat to patient care and population health and there is a growing need for novel therapies to tackle AMR. Bacteriophage (phage) therapy is a re-emerging antimicrobial strategy with the potential to transform how bacterial infections are treated in patients and populations. Currently, in the UK, phages can be used as unlicensed medicinal products on a ‘named-patient’ basis. We make an ethical case for why it is crucially important for the UK to invest in Good (...) Manufacturing Practice (GMP) for both ongoing unlicensed and future licensed phage therapy. Access to phages produced to GMP (GMP phages) will ensure effective patient care and better outcomes as well as health systems benefits. The UK also has the potential to become a global leader in the timely and cost-efficient manufacturing and supply of a therapy that meets internationally recognised standards. (shrink)

Shaḥrūr, Muḥammad; Islamic philosophy; Qurʼan; hermeneutics; criticism, interpretation, etc.

Contributed research papers on Vedic literature and Hindu philosophy.

Medical-legal partnership (MLP) embeds attorneys and paralegals into care delivery to help clinicians address root causes of health inequities. Notwithstanding decades of favorable outcomes, MLP is not as well-known as might be expected. In this essay, the authors explore ways in which strategic alignment of legal services with healthcare services in terms of professionalism, information collection and sharing, and financing might help the MLP movement become a more widespread, sustainable model for holistic care delivery.

D. D. Raphael; VI*—Hume and Adam Smith on Justice and Utility, Proceedings of the Aristotelian Society, Volume 73, Issue 1, 1 June 1973, Pages 87–104, https://d.

Many studies examine a stressors-professional burnout (PB) relation, but only few consider the role of ethical conflicts (ECs) in this context. The aim of this study was to characterize ECs' frequency and level of burden with them among nurses and to establish the relations between ECs' frequency, burden and PB. One hundred nurses participated in this study. ECs' frequency and burden were tested with an originally developed questionnaire. PB was examined with Maslach Burnout Inventory. Most frequent ECs concerned a nurse-patient (...) relationship. PB was positively related to ECs' frequency (r = .54; p = .001) and burden (r = .22; p = .03). Frequency of specific conflict did not imply burden with it and vice versa. ECs' frequency seems more important for PB than a level of burden with them. The most frequent and the most burdening conflicts may lead to development of PB but the less frequent and less burdening ones are also dangerous. (shrink)

Philosophers of technology are not playing the public role that our own theoretical perspectives motivate us to take. A great variety of theories and perspectives within philosophy of technology, including those of Marcuse, Feenberg, Borgmann, Ihde, Michelfelder, Bush, Winner, Latour, and Verbeek, either support or directly call for various sorts of intervention—a call that we have failed to heed adequately. Barriers to such intervention are discussed, and three proposals for reform are advanced: post-publication peer-reviewed reprinting of public philosophy, increased emphasis (...) on true open access publication, and increased efforts to publicize and adapt traditional academic research. (shrink)

Physicalists motivate their position by posing a problem for the opposition: given the causal completeness of physics and the impact of the mental (or, more broadly, the seemingly nonphysical) on the physical, antiphysicalism implies that causal overdetermination is rampant. This argument is, however, equivocal in its use of 'physical'. As Scott Sturgeon has recently argued, if 'physical' means that which is the object of physical theory, completeness is plausible, but the further claim that the mental has a causal impact on (...) the physical is no longer so evident. In this paper I assess the damage due to the ambiguity of 'physical' and provide a repair to the overdetermination strategy. (shrink)

D. J. Allan; XV—Aristotle's Criticism of Platonic Doctrine Concerning Goodness and The Good, Proceedings of the Aristotelian Society, Volume 64, Issue 1, 1 June.

A central theme in western philosophy was to find formal methods that can reliably discover empirical relationships and their explanations from data assembled from experience. As a philosophical project, that ambition was abandoned in the 20th century and generally dismissed as impossible. It was replaced in philosophy by neo-Kantian efforts at reconstruction and justification, and in professional statistics by the more limited ambition to estimate a small number of parameters in pre-specified hypotheses. The influx of “big data” from climate science, (...) neuropsychology, biology, astronomy and elsewhere implicitly called for a revival of the grander philosophical ambition. Search algorithms are meeting that call, but they pose a problem: how are their accuracies to be assessed in domains where experimentation is limited or impossible? Increasingly, the answer is through simulation of data from models of the kind of process in the domain. In some cases, these innovations require rethinking how the accuracy and informativeness of inference methods can be assessed. Focusing on causal inference, we give an example from neuroscience, but to show that the model/simulation strategy is not confined to causal inference, we also consider two classification problems from astrophysics: identifying exoplanets and identifying dark matter concentrations. (shrink)

يغتر بنو آدم بما يسوقه الله إليهم من حلمٍ وعفو عن سوء صنيعهم وجُرم ما اقترفت أيديهم...يغترون بحلم الله...يغرهم جهلهم..ويدفعهم طيشهم إلى إعلان الحرب على الوجود كله حتى على الله ذاته، وجهوا إلى إرادته سبحانه سهام حرابهم، وسوء مكرهم..ولعنات خداعهم..قتلوا الإنسان صنع الله...حاربوا الله باسم الله...أضاعوا الدين..كل الدين باسم الدين...قتلوا العدل فى محرابه عاكفًا يصلى لربه باسم العدالة..هتكوا عرض الإنسانية ثم جلسوا يمصون دمائها بأيديهم الآثمة..ويكأنهم لم يقدموا لها سوءًا..ويكأنهم بقتلها أحسنوا إليها صنيعًا.. يالسوء ماقدمت الإنسانية لبنى الإنسان، يالسوء ما (...) خلفوا ربهم بعد ميثاقه الأول والأشهر، فكانوا النموذج الأسوأ للخلافة، والصورة المضادة تمامًا لطبيعة المستخلف وجوهر إرادته، فما تركوا حرابًا ولا ظلمًا ولا إثمًا إلا اقترفوه، وما تركوا جراحًا ملتاثة بلعينهم إلا وأوسعوها جرحًا وأوغروها نزقًا وأعمقوها حزنًا فكانت تلك هى مكتسباتهم ، فى حين كانت إرادة السماء رحمات الأرض وأمنها وسلامها...ولكنهم..ويالذل ما قدموا للإنسانية، أجهزوا عليها صريعة، فطالت سهام قتلهم وحرابهم السماء ذاتها، تلك التى امتدت إليهم بحنوها وعطفها، فلم تسلم من ثورتهم وقتلهم وظلماتهم، فكانوا بحق هم الثائرون ضد الله... (shrink)

D.C. Schindler reminds us that the motto of Villanova consists of three terms: Unitas, Caritas and Veritas. Postmodern philosophy is keen to malign good Veritas as an exercise in oppression, something which must be avoided if we truly want to reach universal care and unity. In opposition to this trend, Schindler illustrates how Desmond’s philosophy is capable of giving truth its dues against the assaults of Vattimo and others, but also and more importantly that truth serves as foundational for unity (...) and care. Building from Desmond’s Intimate Universal, Schindler illustrates how care and unity need an ontological grounding in truth in order to be more than merely superficial. (shrink)

What happened in the aftermath of Caligula's assassination in January A.d. 41 in relation to the client kings of the period has been the subject of a stimulating note by A. A. Barrett. He has argued that a rescission of Caligula's acta invalidated the legal position of the client kings appointed by Caligula, and that Claudius’ regularising of their position has been misunderstood by the ancient literary sources and has given rise to several apparent inconsistencies in their accounts.

Valerius Maximus’ Facta et dicta memorabilia provide an opportunity of seeing how an undistinguished talent responded to the demise of the republic and the establishment of an imperial system. Fergus Millar has argued that we should view Valerius as a contemporary of Ovid, that is as an author influenced by the last years of Augustus and writing in the early years of Tiberius’ reign, but the internal evidence of Facta et dicta memorabilia better fits publication in the early 30s a.d. (...) in the aftermath of Sejanus’ unsuccessful conspiracy. Although this does distance Valerius further from the key years of transition, he is not remote—and because of the relative paucity of prose authors of the period his presentation of the domus Augusta and of Augustus and Tiberius repays attention. (shrink)

The primary meaning of haurire is ‘to take by scooping, to draw’, and it is used of liquids and of solids which pour. The first section of this paper will try to show that this meaning is frequent and sometimes missed by the commentators. The second section will trace the development of other meanings showing that this root is not applied to drinking and swallowing, except metaphorically, until well into the first century A.D., except once in Livy.

Theologien de haut vol et pasteur zele, Guillaume d'Auvergne a ete eveque de Paris de 1228 a 1249. Proche de la cour capetienne et des milieux mendiants de Paris, il a ete temoin et acteur des principaux evenements politiques et culturels qui ont caracterise la vie du royaume et de sa capitale. Ses sermons, au nombre de 582, dont 25 transmis en deux ou trois versions differentes et plusieurs sous la forme de reportationes, sont ici edites pour la premiere fois. (...) Apres les deux premiers volumes consacres aux sermons de tempore, les deux autres proposeront l'edition des sermons de sanctis et de communi sanctorum et de occasionibus.". (shrink)